Mauricio Pochettino has made five changes to the side that lost 2-1 to Wolves last time out.
Thiago Silva and Armando Broja drop to the bench, while Lesley Ugochukwu is not in the squad, and Cole Palmer and Raheem Sterling are suspended for this game.
Moises Caicedo makes a return from illness. Benoit Badiashile, Mykhailo Mudryk get a start, while Christopher Nkunku and Ian Maatsen have also been given their first Premier League start.
See the teams below
Chelsea starting XI: Petrovic; Gusto, Disasi, Badiashile, Colwill; Caicedo, Gallagher; Mudryk, Nkunku, Maatsen; Jackson.
Subs: Bettinelli, Bergstrom, Thiago Silva, Madueke, Broja, Gilchrist, Lavia, Matos, Castledine.
Crystal Palace starting XI: Henderson; Clyne, Andersen, Guehi, Mitchell; Lerma, Richards; Olise, Eze, Ayew; Mateta.
Subs: Matthews, Tomkins, Franca, Schlupp, Hughes, Ahamada, Riedewald, Adaramola, Ozoh.